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  • Chemical Biology

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    adidas NMD Racer

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    Here’s some medicinal chemistry combined with synthetic biology for you. Many people are used to thinking in terms of finding small-molecule probes for various cell targets, and those are valuable things. But what if you want to control a certain population of (for example) ion channels, but there aren’t any compounds that will do the… 2011 NIKE ZOOM KD IV 4 YOTD YEAR OF THE DRAGON 473679 300 Men’s Size 15
  • Chemical News

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    BNIB HUGO BOSS MENS WHITE LEATHER TRAINERS 'FUTURISM' RRP - RARE I was interested to see this paper, which goes into detail on a chemical phenomenon that many have seen but no one understands very well: triboluminescence. That word meets with a blank stare or instant recognition; there’s not much in between. It means “emission of light when a material is physically broken”, and that encompasses… NIKE BASKETBALL KD 5 PRM AUNT PEARL
  • Analytical Chemistry

  • Cancer

    Making and Measuring Multivalency

    Here’s an unusual paper that’s studying receptor behavior on cell surfaces by use of atomic force microscopy. (Here’s the SI file, which is free to access). The authors took the marketed VEGF inhibitor vandetanib (VD6474) and attached it through linkers to the AFM tip, and then scanned around the surface of live human umbilical v… NIKE ZOOM ROOKIE GAME ROYAL PRE-OWNED 472688 403 SIZE 11
  • Drug Assays

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  • Biological News

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    A scientific giant, Sydney Brenner has died at the age of 92. He was present at the beginning of molecular biology – while in the chemistry department at Oxford, he car-pooled with Dorothy Hodgkin, Leslie Orgel, Jack Dunitz and others over to Cambridge to see Watson and Crick’s new model for the structure of DNA… Jordan 1 Med University gold Size 9
  • Business and Markets

  • Analytical Chemistry

    A Close Look at Fragments

    Here’s a look from the D. E. Shaw research team at fragment binding, and even if you don’t do fragment-based drug discovery, it’s worth a read. That’s because the mechanisms by which fragments bind to proteins are most likely the fundamental ones by which larger molecules bind as well; this is the reductionist look at… Read More
  • Analytical Chemistry

  • Academia (vs. Industry)

    Startup Culture, Starting

    Adidas Terrex Swift R2 GTX Men's Hiking shoes Outdoor Sneakers CM7492 Many readers of this blog work in the biopharma industry, naturally, and of those, many are in and around the (few) locations where a great many of the companies in the industry are born. I myself am in the Boston/Cambridge area, famously thick with companies large and small, and then you have the Bay area… ASICS Gel-Quantum 360 Running shoes Sneakers Mens 10.5 Athletic
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